We've been informed that ThinkFilm is in final talks to acquire domestic distribution rights to Billy O'Brein's killer calf movie, Isolation (review), which follows a young couple on the run take refuge at a lonely farm, only to find that the farmer has been supplementing his income by allowing genetic experiments on his cattle. A mutated calf is born and goes on the hunt. Word has it that the film will go directly to DVD with no theatrical release (boo!), we'll keep you posted when official word comes down.