SPOILERS!!!!!
Since they're both dead it won't really be a great sequel. Sequels that don't have the original actors usually go straight to DVD. I'd rather have it be a stand-alone film. It's great like that. If they do make a sequel, it'll either be about a similar couple, prequel to the story, or they go attack some stupid teens. One of those 3. I loved The Strangers, but I really don't think there should be a sequel since they're both dead.
SPOILERS!!!!!